Kyasanur Forest Disease Vaccine

The vaccine for Kyasanur Forest Disease (KFD) consists of an inactivated KFD virus that is produced in tissue-culture and preserved in formalin. The vaccine has a 62% effectiveness rate for individuals who receive two doses. For individuals who receive an additional dose, the effectiveness increases to almost 83%.

In a 1994 study, 61,302 people received two doses of vaccine. No untoward reactions were observed in any of the vaccinated persons.

For the control of outbreaks, the vaccination strategy consists of 2 vaccine doses that are administered at least 1 month apart to persons 7–65 years of age. Vaccine-induced immunity is short-lived, so the first booster dose of vaccine is recommended within 6–9 months after primary vaccination; thereafter, annual booster doses are recommended for 5 years after the last confirmed case in the area.