Crimean-Congo Haemorrhagic Fever CCHF

Crimean-Congo Haemorrhagic Fever (CCHF) is one of several infectious haemorrhagic fevers and is caused by the Crimean-Congo haemorrhagic fever virus. This virus is transmitted to humans through the bite of infected ticks, particularly those of the Hyalomma genus, or through direct handling and preparation of fresh carcasses of infected animals, usually domestic livestock. It can also be acquired through nosocomial transmission (from treatment in a hospital).

The risk for travellers getting CCHF is very low, but this risk is increased for health-care workers and for anyone engaging in animal researchers.

Everyone is susceptible to CCHF, but life-long immunity usually results after recovery from an infection.

CCHF begins with the sudden appearance of fever, weakness, fatigue, irritability, headache and loss of appetite, along with severe pain in the arms and legs. There may be vomiting, diarrhoea and abdominal pain. A tiny haemorrhagic rash begins in the mouth, chest and abdomen and spreads to the rest of the body. Bleeding may occur from the gums, nose, lungs, intestines, uterus, and in the urine. Heavy bleeding occurs only in the most severe cases associated with liver damage. The fever continues for 5 to 12 days and recovery is prolonged. Between 2 to 50 percent of people with CCHF die depending on the severity of the illness.

There is no specific treatment for CCHF. There is a vaccine used in Eastern Europe and Russia but it is not available in North America. The use of an anti-viral medicine called ribavirin, as well as the administration of antibodies from a recovering patient, may be useful.

The disease is found in Eastern Europe, particularly in the former Soviet Union (Kazakhstan, Uzbekistan, southern Russia), throughout the Mediterranean, in northwestern China, central Asia, southern Europe, tropical and southern Africa, the Middle East (including the Arabian Peninsula), and the Indian subcontinent. CCHF occurs in Albania, Bosnia, Herzegovina, Bulgaria, Iraq, and Pakistan.